BodyPharm CJC-1295 & Ipamorelin 20 Pen

CJC-1295 & Ipamorelin 20 Pen?

The Body Pharm CJC-1295 & Ipamorelin 20 Pen is a premium dual-peptide growth hormone support formula designed to optimise recovery, lean muscle development, fat metabolism and overall performance. Each prefilled pen contains: 10 mg CJC-1295 + 10 mg Ipamorelin(Total peptide content: 20 mg)

What does it do?

• The pen delivers 10 mg CJC-1295 + 10 mg Ipamorelin in a prefilled dial-a-dose format; dialling 200 mcg gives 200 mcg of each peptide, not 200 mcg combined.
• Standard dosing is 100–200 mcg once daily before sleep on an empty stomach; cycles run 8–12 weeks on, 4 weeks off.
• Expected benefits include deeper sleep within 1–2 weeks, improved recovery by week 3–4 and visible body composition changes from week 6–8 onward.
• Side effects are typically mild and localised (injection-site redness, transient water retention, tingling).

Who is this for?

• Adults researching growth-hormone support
• Those focused on recovery, lean muscle and sleep

How CJC-1295 and Ipamorelin work together

CJC-1295 and Ipamorelin stimulate two different receptors on the pituitary simultaneously. That dual-receptor activation produces a larger GH pulse than either peptide alone.

CJC-1295 is a synthetic Growth Hormone Releasing Hormone (GHRH) (1-29) analogue that binds the GHRH receptor. Ipamorelin is a selective Growth Hormone Releasing Peptide (GHRP) and ghrelin-mimetic that binds the GHSR-1a ghrelin receptor. Combined, they raise both the frequency and amplitude of natural GH release.

Once injected, the sequence runs like this:

• CJC-1295 docks at the GHRH receptor on pituitary somatotrophs and signals them to prepare a GH pulse.
• Ipamorelin docks at the ghrelin receptor (GHSR-1a) on the same cells and amplifies the size of that pulse.
• The pituitary releases stored endogenous GH in a pulse pattern that mimics natural physiology, rather than producing a flat, supraphysiological level.
• The liver responds to the GH pulse by producing IGF-1 (Insulin-like Growth Factor 1), the downstream mediator most fat-loss and recovery claims hinge on.
• GH returns to baseline within hours, preserving the normal pulsatile rhythm and negative-feedback loop.

Ipamorelin is reported to have minimal effect on cortisol and prolactin compared with older GHRPs like GHRP-2 and GHRP-6, because its receptor selectivity is narrower than earlier-generation compounds.

How to use the Body Pharm Pen

Remove the pen from the fridge, dial your dose, inject subcutaneously into the abdomen, and return it to the fridge. These steps apply only to the Body Pharm CJC-1295 & Ipamorelin 20 Pen, not to vial-and-syringe products.

1. Remove the pen from the refrigerator 5–10 minutes before injecting. Cold peptide solution stings going in. Let it reach room temperature on a clean surface.
2. Wipe the injection site with an alcohol swab. The lower abdomen, two finger-widths from the navel, is the standard subcutaneous injection site because this area has consistent subcutaneous depth and minimal nerve density.
3. Attach a fresh pen needle and prime if the pen is new. Discard a 1–2 mcg test drop on first use to clear air from the cartridge.
4. Dial your dose. On the Body Pharm pen, dialling 200 mcg delivers 200 mcg CJC-1295 plus 200 mcg Ipamorelin in the same shot. Dialling 300 mcg delivers 300 mcg of each peptide, not 300 mcg total. Read this twice before your first injection.
5. Pinch a fold of subcutaneous tissue at the swabbed site. This lifts the fat layer away from muscle, ensuring the needle deposits into subcutaneous tissue rather than intramuscular space.
6. Insert the needle at 45–90 degrees and press the plunger slowly. Hold for 5–10 seconds after the dial returns to zero so the full dose deposits.
7. Withdraw the needle and apply light pressure with a clean tissue. No massage. A small bead of blood is normal.
8. Remove and bin the needle in a sharps container, then return the pen to the fridge immediately.

CJC-1295 & Ipamorelin Dosing Guide (2026)

A typical Body Pharm pen dose is 100–200 mcg of each peptide per injection for beginners, rising to 200–300 mcg of each for maintenance, administered subcutaneously once daily, 30–60 minutes before sleep on a 2–3 hour empty stomach. This timing stacks the peptide pulse onto the body’s natural nocturnal GH wave. Cycles usually run 8–12 weeks on, 4 weeks off. This guidance is practitioner consensus, not a SAHPRA-registered protocol [unverified].

Recommended dosing protocol

1. Week 1–2 (assessment): Dial 100 mcg. This delivers 100 mcg CJC-1295 + 100 mcg Ipamorelin. Watch for flushing, head-rush, or unusual hunger.
2. Week 3 onward (standard): Dial 200 mcg once daily. Most adult users settle here because this dose produces measurable GH elevation without excessive side effects.
3. Advanced (week 4+): Dial up to 300 mcg if tolerated and clinically appropriate. Going above 300 mcg per shot offers diminishing GH-pulse returns and raises side-effect risk [unverified].
4. Cycle: Run 8–12 weeks, then take 4 weeks off to let receptor sensitivity reset. A 4-week minimum off-cycle is the figure cited in local SA peptide pricing pages [unverified].

Injection timing

Inject 30–60 minutes before bed on a relatively empty stomach (2–3 hours after your last meal). Food, especially carbs and fats, blunts GH release by raising insulin and free fatty acids, which suppress GHRH signalling [unverified]. Post-workout is a viable secondary slot if bedtime dosing does not suit your schedule. Keep at least two hours between food and injection either way.

Important dosing points

• The dial values above apply only to the Body Pharm CJC-1295 & Ipamorelin 20 Pen. Do not transfer this scheme to vials, compounded syringes, or other pen products.
• No 2020–2026 randomised trial confirms specific body-composition outcomes from CJC-1295 + Ipamorelin combined [unverified]. Dose claims rest on mechanistic reasoning and clinic experience.
• Consult a registered GP or endocrinologist before starting, particularly if you have diabetes, active cancer, or take thyroid or corticosteroid medication.
  Body recomposition responses vary with training status, protein intake, and sleep quality

Possible side effects

The most commonly reported side effects of CJC-1295 and Ipamorelin are mild and localised: injection site redness, transient water retention, early-cycle lethargy, and tingling or numbness in the hands. Elevated GH can cause fluid shifts and temporary nerve compression [unverified]. These tend to settle within the first 1–2 weeks as the body adjusts to elevated GH pulses [unverified].

Less frequently reported effects include headache, facial flushing shortly after injection (from vasodilation), vivid dreams (from increased slow-wave sleep), and mild appetite increase from the ghrelin-receptor activity of Ipamorelin [unverified]. If symptoms persist past two weeks or worsen, drop the dose or stop and consult a doctor.